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Kennedy R Lees Selected Research

disufenton sodium (NXY 059)

6/2008NXY-059 for the treatment of acute stroke: pooled analysis of the SAINT I and II Trials.
8/2007NXY-059 for the treatment of acute ischemic stroke.
8/2007Safety and tolerability of NXY-059 for acute intracerebral hemorrhage: the CHANT Trial.
12/2006Additional outcomes and subgroup analyses of NXY-059 for acute ischemic stroke in the SAINT I trial.
2/2006NXY-059 for acute ischemic stroke.
1/2005Population pharmacokinetic modelling and estimation of dosing strategy for NXY-059, a nitrone being developed for stroke.

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Kennedy R Lees Research Topics

Disease

126Stroke (Strokes)
01/2021 - 01/2003
72Ischemic Stroke
01/2021 - 05/2002
14Cerebral Hemorrhage
01/2020 - 05/2005
13Hemorrhage
12/2020 - 08/2007
13Atrial Fibrillation
12/2020 - 01/2003
8Intracranial Hemorrhages (Intracranial Hemorrhage)
01/2021 - 08/2003
8Heart Failure
01/2018 - 08/2007
7Infarction (Infarctions)
05/2009 - 05/2002
4Hypertension (High Blood Pressure)
06/2012 - 08/2007
3Infections
09/2018 - 07/2003
3Myocardial Infarction
06/2016 - 08/2003
3Cardiovascular Diseases (Cardiovascular Disease)
09/2013 - 08/2003
2Hematoma
01/2020 - 01/2019
2Pneumonia (Pneumonitis)
10/2019 - 10/2014
2Embolic Stroke
01/2019 - 08/2015
2Arterial Occlusive Diseases (Arterial Occlusive Disease)
03/2018 - 12/2013
2Left Ventricular Dysfunction
01/2018 - 06/2016
2Diabetes Mellitus
04/2015 - 03/2013
2Transient Ischemic Attack
08/2013 - 06/2012
2Carotid Stenosis (Carotid Artery Stenosis)
08/2012 - 05/2005
2Body Weight (Weight, Body)
06/2012 - 09/2008
1Nervous System Diseases (Neurological Disorders)
01/2020
1Deglutition Disorders (Dysphagia)
10/2019
1Arteriovenous Fistula
01/2019
1Leukoaraiosis
01/2019
1Fever (Fevers)
09/2018
1Thrombosis (Thrombus)
01/2017
1Ischemia
12/2015

Drug/Important Bio-Agent (IBA)

39Tissue Plasminogen Activator (Alteplase)FDA Link
01/2020 - 11/2003
264- Acetamido- 4'- isothiocyanatostilbene- 2,2'- disulfonic Acid (SITS)IBA
01/2021 - 01/2007
10AnticoagulantsIBA
12/2020 - 08/2007
8Neuroprotective AgentsIBA
11/2014 - 05/2005
7Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
06/2017 - 05/2002
6Biomarkers (Surrogate Marker)IBA
01/2021 - 05/2008
6Glucose (Dextrose)FDA LinkGeneric
01/2020 - 03/2003
6Antihypertensive Agents (Antihypertensives)IBA
01/2018 - 05/2004
6Pharmaceutical PreparationsIBA
04/2015 - 12/2002
6disufenton sodium (NXY 059)IBA
06/2008 - 01/2005
6Free RadicalsIBA
06/2008 - 01/2005
63- (2- ((phenylamino)carbonyl)ethenyl)- 4,6- dichloroindole- 2- carboxylic acidIBA
01/2006 - 10/2003
6Glycine (Aminoacetic Acid)FDA LinkGeneric
01/2006 - 10/2003
5Uric Acid (Urate)IBA
08/2012 - 08/2003
4Nitric Oxide (Nitrogen Monoxide)FDA Link
01/2018 - 01/2009
4Insulin (Novolin)FDA Link
03/2017 - 03/2003
4Blood Glucose (Blood Sugar)IBA
02/2012 - 06/2008
3Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
03/2020 - 04/2016
3Vitamin KFDA Link
01/2020 - 06/2017
3Folic Acid (Vitamin M)FDA LinkGeneric
08/2013 - 06/2012
3Vitamin B Complex (B Vitamins)IBA
08/2013 - 06/2012
3TabletsIBA
08/2013 - 06/2012
3Vitamin B 6IBA
08/2013 - 06/2012
3Vitamin B 12 (Cyanocobalamin)FDA LinkGeneric
08/2013 - 06/2012
3Desmodus rotundus salivary plasminogen activator alpha 1IBA
01/2010 - 01/2005
3Allopurinol (Remid)FDA LinkGeneric
11/2009 - 12/2008
3MagnesiumIBA
05/2009 - 01/2006
2boldenone undecylenate (Equipoise)IBA
10/2018 - 06/2017
2Nitroglycerin (Dynamite)FDA LinkGeneric
01/2018 - 01/2016
2Digoxin (Digitek)FDA LinkGeneric
01/2018 - 04/2016
2apixabanIBA
11/2017 - 06/2017
2Warfarin (Coumadin)FDA LinkGeneric
06/2017 - 08/2013
2Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA
06/2016 - 01/2005
2Angiotensin Receptor AntagonistsIBA
06/2016 - 05/2004
2Rosuvastatin Calcium (Crestor)FDA Link
12/2015 - 04/2015
2VitaminsIBA
08/2013 - 06/2012
2HomocysteineIBA
08/2013 - 06/2012
2Clopidogrel (Plavix)FDA Link
06/2012 - 05/2005
2PerindoprilFDA LinkGeneric
06/2006 - 01/2005
2UK279276IBA
11/2003 - 07/2003
1Low-Molecular-Weight Heparin (Heparin, Low Molecular Weight)IBA
01/2019
1Ceftriaxone (Ceftriaxon)FDA LinkGeneric
09/2018
1Metoclopramide (Reglan)FDA LinkGeneric
09/2018
1Acetaminophen (Paracetamol)FDA LinkGeneric
09/2018
1DabigatranFDA Link
11/2017
1RivaroxabanIBA
11/2017
1aliskirenFDA Link
06/2016
1Captopril (Capoten)FDA LinkGeneric
06/2016
1AngiotensinsIBA
06/2016
1Renin InhibitorsIBA
06/2016
1ReninIBA
06/2016
1Valsartan (Vals)FDA Link
06/2016
1danaparoid (Orgaran)FDA Link
04/2016
1Nitric Oxide DonorsIBA
01/2016
12,6-dinitrotoluene (DNT)IBA
05/2015
1Brain Natriuretic Peptide (Natrecor)FDA Link
04/2015
1salicylhydroxamic acid (SHAM)IBA
11/2014
1BenzodiazepinesIBA
10/2014

Therapy/Procedure

35Therapeutics
12/2020 - 11/2003
9Thrombectomy
01/2021 - 12/2013
9Secondary Prevention
01/2020 - 05/2004
9Thrombolytic Therapy
01/2020 - 01/2007
6Treatment Delay
09/2016 - 11/2014
5Time-to-Treatment
08/2016 - 05/2010
3Contraindications
12/2015 - 06/2006
2Stents
01/2021 - 08/2015
2Length of Stay
10/2019 - 04/2013
2Induced Hypothermia
09/2019 - 07/2014
1Critical Care (Surgical Intensive Care)
10/2019
1Minimally Invasive Surgical Procedures
01/2019
1Aftercare (After-Treatment)
11/2014
1Laser Therapy (Surgery, Laser)
11/2014